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At the same time, GLP-1 receptor activation reduces the activity of pathogenic Th1 and Th17 cells, the effector T cells most directly responsible for autoimmune tissue damage

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Hossain argues the real cause isnt nature, its political negligence

In the STEP and SURMOUNT trial programs, participants treated with semaglutide and tirzepatide respectively achieved average weight reductions of 15 to 22% of total body weight, losses that had previously been achievable only through bariatric surgery [8,9]

Both GLP-1 and GIP have a short half-life because of their rapid inactivation by DPP-4 enzyme

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